Equipment

The Sammons BrainHealth Imaging Center houses two Siemens 3T Prisma scanners utilizing Syngo MR E11 software.  The design and field strength are optimized for functional MRI (fMRI), providing crisp anatomical detail and a signal-to-noise ratio that reduces distortion to facilitate the acquisition and interpretation of data.

Each scanner has a 60-cm bore and is capable of accommodating up to 204 connected coil elements and 64 RF channels, with three coil configurations available for imaging: a 20-channel (16 head, 4 neck) DirectConnect head/neck coil, a 32-channel head coil, and a 64-channel (40 head, 24 neck) DirectConnect/SlideConnect coil with opening for a 128-lead EEG.  The maximum gradient amplitude is 80 mT/m, with a slew rate of 200 T/m/s, allowing for fast ramp times to strong gradients, both of which are vital to spatial and temporal resolution.

Our centralized control room was designed to accommodate information exchange between personnel, especially during sequence and protocol development as well as maintenance procedures. The focus of this set-up was also to allow for simultaneous scanning procedures such as Hyperscanning – a neuroimaging technique that measures brain activity of two participants at the same time (with the two scanners are operating synchronously), allowing researchers to study how their brains interact during social interactions.

Additionally, the Siemens Prisma scanners are capable of employing CAIPIRINHA for use in breath-hold experimental designs, and BLADE for rotational k-space sampling.  These scanners feature TimTX/ZOOMit for parallel transmit capabilities and B1 shimming to reduce shading artifacts and improve image quality, iPAT² (integrated Parallel Acquisition Techniques) for simultaneous parallel imaging in 3D sequences in the phase encoding and 3D direction.

The stimulus presentation system available in both scanners provides projection of visual stimuli utilizing a high-resolution, long-life triple LED light source with a custom-designed, and mounted long-throw lens.  Stimuli are projected onto a Velcro-mounted screen inside the scanner bore.  Delivery of auditory stimuli occurs through stereophonic (dual-channel), air-coupled piezoelectric transducers surrounded by disposable bud-style canal tips that include passive noise reduction (28 dB attenuation).  Each control room console unit includes amplifiers (with equalization), audio level with peak-detection limiters, and a multi-port video and audio input switch and multi-output VGA coupler (mirrors screen projection to a monitor in the scanner control room). 

Participant responses are captured with non-magnetic, non-electronic response switches with up to five channels for multi-response paradigms, and a sixth channel processes triggering of the stimulus paradigm by the scanner once dummy scans are complete.  Response switches and stereophonic earphones utilize optical fiber cables to transmit signal to the scanner control room.  There are two MR compatible state-of the-art Eyelink 1000+ eyetrackers (SR Research) equipped with 2000Hz high-speed fiber-optic cameras available.

Additionally, the center is equipped with 2 BIOPAC MP160 data acquisition and analysis systems (Biopac Systems, Inc.) fully integrated with the Siemens MR scanners. The BIOPAC system with AcqKnowledge software + Basic Scripting is an Ethernet-ready modular data acquisition and analysis unit can record multiple (up to 16) channels with differing sample rates at speeds up to 400 kHz. The AcqKnowledge Acquisition & Analysis Software is integrated with the BIOPAC modules, allowing users to view, measure, transform, analyze, and report data.

BIOPAC modules are available to perform
the following measurements:
  • electrical activity generated by the heart (normal ECG output and R-wave detection);
  • skin conductance level (SCL) and skin conductance response (SCR);
  • respiration (thoracic or abdominal);
  • adult human pulse oximetry;
  • SpO2 CO2 content in ambient air, expired breath, and in breathing gas;
  • heart rate (HR) data
  • relative central arterial pressure (providing noninvasive “Beat-by-Beat” Blood Pressure); and

Additional Equipment

MRI Simulator

A generous gift from the Sapphire Foundation provided an opportunity to acquire the Psychology Software Tools MRI Simulator™.  This resource provides researchers an opportunity to introduce participants (from infants to elderly) to the MRI environment and get them more comfortable prior to research/scan procedures.

SimFx™ MRI Auditory Simulation Software delivers active ambient and scanner noises. 

MoTrak® Head Motion Tracking System has been used by several studies scanning autistic adolescents and adults to prepare them for tasks conducted in the bore and train them to reduce movement.

Optoacoustics FOMRI-III™+ Noise-Cancelling Microphone

coil-mounted microphone for highest real-time speech quality recording & speech synchronization

RespirAct® Sequential Gas Delivery (SGD) system (Thornhill Medical)

Computer-controlled gas blender used to provide accurate, repeatable, non-invasive control of blood gases to stimulate vascular reactivity. It monitors blood flow responses in conjunction with diagnostic imaging techniques to show areas of hemodynamic compromise.

Sensimetrics Acoustic Delivery System

High-quality acoustic in-ear stimulus delivery w/ calibrated sound attenuation; fit within any head coil.  Frequency response equalization is achieved by pre-filtering stored digital stimuli. Equalization filters are provided and can be used within Matlab.